Section I. Clinical, Laboratory, and Radiological Features Epidemiology


1. Clinical Features and Differential Diagnosis
2. Prognosis and Clinical Course
3. Clinical and Laboratory Measures of Disease
4. Diagnostic Autoantibodies
5. Plain Radiography
6. Measurement of Radiological Outcomes
7. Ultrasonography and MRI


Section II. Section III. Pathogenesis


8. Genetics
9. Overview of Pathogenesis
10. Synovial Tissue Pathology
11. Cytokines
12. Leukocyte Recruitment and Angiogenesis
13. Neutrophils and Inflammation
14. Cellular and Humoral Immunity in Synovitis
15. Autoimmunity
16. Complement and Innate Immunity
17. Synoviocyte Proliferation
18. Bone and Cartilage Destruction
19. The Role of T Cells
20. Animal Models


Section IV. Therapy


21. Approach to Therapy
22. NSAIDS and Analgesics
23. Corticosteroids (Systemic and Intra-articular)
24. Methotrexate and Azathioprine
25. Sulfasalazine
26. Gold Compounds, Hydroxychloroquine, D-Penicilamine, Bucillamine, and
Azathioprine
27. Minocycline
28. Cyclosporine
29. Leflunomide
30. Infliximab and Adalimumab
31. Etanercept
32. Anakinra
33. Staphylococcal Protein A
34. Combination DMARD Therapy
35. Treatment of Early Disease


Section V. Non-Pharmacologic Therapy


36. Behavioral Therapy
37. Occupational Therapy
38. Surgery


-Total Joint Arthroplasty

-Hand and Wrist Surgery

-Foot and Ankle Surgery

-Cervical Spine Surgery

39. Special Management Issues

-Treatment of Extra-Articular Disease

-Osteoporosis

-Depression

-Web-based Resources for Continuing Education